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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPN14 All Species: 18.79
Human Site: S327 Identified Species: 41.33
UniProt: Q15678 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15678 NP_005392.2 1187 135261 S327 R Q P T W S R S S L P R Q Q P
Chimpanzee Pan troglodytes XP_001171329 1187 135241 S327 R Q P T W S R S S L P R Q Q P
Rhesus Macaque Macaca mulatta XP_001106167 1187 135194 S327 R Q P T W S R S S L P R Q Q P
Dog Lupus familis XP_849236 1187 134903 S327 R Q P T W S R S S L P R Q Q P
Cat Felis silvestris
Mouse Mus musculus Q62130 1189 135012 S327 R Q P T W S R S S L P R Q Q P
Rat Rattus norvegicus Q62728 1175 133393 K333 S S R M S L P K P Q P Y A M P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511302 1193 135259 Q332 S R S S L P R Q Q P Y I M P P
Chicken Gallus gallus XP_419419 1191 135566 Q332 S R S S L P R Q H P F I L P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339962 834 94004 Y22 Y T S S Q D F Y C K E I K F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P28191 1026 115075 H214 A E Q N F L D H A R R L E M Y
Sea Urchin Strong. purpuratus XP_796215 1318 147575 L338 V V D P E R R L S M D G Q Q M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.9 95.6 N.A. 91.5 53.7 N.A. 87.9 84.9 N.A. 32.8 N.A. N.A. N.A. 24.7 34.5
Protein Similarity: 100 99.7 99.5 97.2 N.A. 95.6 70.7 N.A. 92.1 91.5 N.A. 48.1 N.A. N.A. N.A. 42 51.7
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 13.3 13.3 N.A. 0 N.A. N.A. N.A. 0 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 26.6 26.6 N.A. 13.3 N.A. N.A. N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 10 0 0 0 10 0 0 0 0 % D
% Glu: 0 10 0 0 10 0 0 0 0 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 0 0 10 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 10 0 0 10 0 0 % K
% Leu: 0 0 0 0 19 19 0 10 0 46 0 10 10 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 10 0 0 10 19 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 46 10 0 19 10 0 10 19 55 0 0 19 73 % P
% Gln: 0 46 10 0 10 0 0 19 10 10 0 0 55 55 0 % Q
% Arg: 46 19 10 0 0 10 73 0 0 10 10 46 0 0 0 % R
% Ser: 28 10 28 28 10 46 0 46 55 0 0 0 0 0 0 % S
% Thr: 0 10 0 46 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 46 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 10 0 0 10 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _